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The mechanism likely involves both the opiate receptor effects and DSIP's normalization of stress hormones, which become dysregulated during addiction and withdrawal

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In addition, acetylation also regulates several other key cell cycle regulators, including protein kinase BUBR1, Aurora kinase A, Aurora kinase B, Cyclin-Dependent Kinase 1 (CDK1), CDK2, and PLK4, to modulate the cell cycle [30]

& Shong, H
