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ROS induces oxidative stress in cells and potentially damages neurons

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tremor-dominant Parkinson's disease generally progresses more slowly and causes a decreased functional disability compared to non-tremor-dominant Parkinson's disease [7]

This intricate crosstalk highlights the interconnectedness of the gut-brain axis, where disruptions in microbial balance (dysbiosis) or microglial dysfunction can contribute to neurodegenerative and neuroinflammatory disorders Figure 1

Dosedependent antiinvasive activity of baicalin was observed in OC2 human oral cancer cells and MDAMB231 human breast cancer cells, accompanied by downregulation of MMP2, MMP9, and uPA [108, 109]

doi: 10.1161/res.133.suppl_1.P3193 28 DeBerardinisRJChengT