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If you want to optimise your microneedling protocol: The data suggests that longer treatment duration (36 months minimum) and less aggressive session frequency (fortnightly rather than weekly) may actually produce better results than trying to do more, more often

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Namely, isoprenaline interacts with the NO system and its blockade [38,41,42,43]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Yue X., Liu S.L., Guo J.N., Meng T.G., Zhang X.R., Li H.X., Song C.Y., Wang Z.B., Schatten H., Sun Q.Y., et al