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(2009) 18:R16976

Developmental toxicity of brominated flame retardants, tetrabromobisphenol A and 1,2,5,6,9,10-hexabromocyclododecane, in rat offspring after maternal exposure from mid-gestation through lactation

The decision between combination and single-compound dosing should follow from the research question rather than from a default assumption that more compounds are better
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These data support the calculation of the Maximum Recommended Starting Dose (MRSD) the starting dose for the first administration in humans, derived from preclinical data and converted to a human equivalent dose using internationally agreed methods

CBP officers deal with medication declarations routinely, and transparent declarations almost always result in smooth processing
