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Description
For researchers exploring metabolic health, these glucose-regulating effects complement the fat loss benefits and suggest 5-amino-1mq could be valuable in protocols targeting metabolic dysfunction

Male, 18-week-old C57BL/6J mice, maintained on a 60% high-fat diet (HFD
In vitro , NNMTi significantly decreased the intracellular production of MNAM, increased the intracellular levels of NAD + , and inhibited adipogenesis
Some participants achieved weight loss of approximately 24% of body weight at 48 weeks approaching levels reported with some bariatric surgical procedures, though no direct head-to-head comparisons have been conducted and long-term durability beyond the trial period remains unknown

2013;8:e71272

Kraus D, et al
