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One study states that topical verapamil applied for 9 months decreases penile curvature in 61.1% of participants, with plaque size reduction in 84% of them, pain reduction in 100%, and improvement in the quality perception of erection in 81% of patients 26

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The higher sensitivity of the sebaceous cells to androgens, leading to an increase in cellular proliferation may be a possible cause of penile SH.[3] There are several cases of SH of genital location in adults,[4] not only in the penis but also in the vulva.[5] Some of them show a typical linear pattern of distribution,[4] which has been interpreted as a Koebner phenomenon or induced by cosmetics.[4,6] Dermoscopy shows yellow and white aggregates at the center of the lesion

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Comparative oxidative metabolism in mammalian sperm

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