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The gap in the logic is the same one as with methionine: correcting a deficiency is not the same as producing weight loss in someone who is replete

Leukemia (2015) 29:40614

Keeping homocysteine in a healthy range through adequate B12, folate, and B6 doesn't guarantee you won't experience mood problems

Zonisamide for weight loss in obese adults: a randomized controlled trial

In the case of methylcobalamin, B12 is attached to a methyl group

Signs of Anemia Anemia is a common sign of vitamin B12 deficiency