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S., Ooi, C

The highly vascular nature of the tissue and the intimate contact between blood and hepatocytes, which contain the xenobiotic-metabolizing enzymes, allows for the rapid diffusion of chemicals in and metabolites out

Next, the OD 500 of OP50 cultures, with or without added drugs, were measured at 0, 3, 6, and 18 h at 37 C, using an Infinite 200 PRO microtiter plate reader (Tecan)

These findings and others [96, 97] have led to the hypothesis of a receptor barcode [95, 97, 98]

Medium was changed after 2 days and cells were split after reaching a confluence of 8090%

The identification of these has been the subject of work from hundreds of laboratories around the world over many years