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Each additional year of metformin use raised the odds of B12 deficiency by 13%, and neuropathy was more prevalent among metformin users with low B12

In addition to its potential as a therapeutic agent for neurological disorders and cancer treatment, SFN has shown promise as a potential treatment for cerebral ischemic injury and intracranial hemorrhage

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High levels indicate megaloblastic anemia associated with deficiencies in folate or B12
