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These include microdontia ( n = 6), agenesis of several permanent teeth ( n = 3), and tooth discoloration ( n = 3)

In agreement with glutamine being the primary source of glutamate in the cell, exposure of cells to the uniformly labeled 13 Cglutamine shows a pattern of enrichment of five 13 C carbons in glutathione

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Author Contributions Conceptualization, N.P

Furthermore, renal tubule-specific deficiency of Acsl4 conferred significant protection against oxalate-induced AKI, as evidenced by alleviated structural and functional renal damage, reduced oxidative stress and decreased inflammatory cell infiltration, all of which collectively contribute to a reduction in ferroptosis