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Clinical and Molecular Hepatology

Chalcone synthase is the first committed enzyme in the plant flavonoid biosynthesis pathway, yet shows low product specificity in vitro

This combination supports antioxidant function and maintains glutathione stability within the body

In young adult mice on a high-fat diet, MOTS-c also activated muscle AMPK and increased GLUT4 levels, leading to better glucose uptake in muscle and prevention of fat accumulation
