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They are important for a myriad of biological functions including, inflammation (Li et al., 2000), opioid analgesia (Bianchi et al., 2009

Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimers disease

Under OS, conformational changes in Keap1 following its Cys oxidation lead to its dissociation from the Nrf2-Keap1 complex and to the translocation of free Nrf2 into the nucleus

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