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The Combined Assessment of Function and Survival (CAFS): a new endpoint for ALS clinical trials

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It is also used for treatment of various chronic or acute issues such as chest pain, heart failure, high levels of fat or cholesterol in the body, kidney failure, male infertility, PCOS among many others

For advanced mitochondrial support formulas, ALA and CoQ10 can also be combined, but brands must evaluate dosage form, absorption, stability, cost and compliant claim language before production

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High-dose antioxidant supplements (vitamins C and E in megadoses) lack evidence for benefit in diabetes management and may interfere with certain laboratory tests or medications
