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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Cheng B, Yang X, An L, Gao B, Liu X, Liu S
This section introduces principles of bioavailability , consequences of first-pass elimination , and the relationship between bioavailability and the hepatic extraction ratio
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This modification is carried out by the histone methyltransferases Suv39h in mammals, Su(var)3-9 in Drosophila, and Clr4 in yeast
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