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It involves nerve damage which can occur in different parts of the body along with the symptoms associated with it
mHTT disrupts mitochondrial function, leading to iron (Fe 2+ ) accumulation in striatal neurons, Fenton reaction-induced ROS, and lipid peroxidation
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Jan 2011;18(1):63-72
doi: 10.1016/j.intimp.2022.109607 58 ChengHPFengDDLiXHGaoLHQiuYJLiangXYet al
