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however, it is originally colonized by the oropharynx and microaspirations from the gastrointestinal tract

Rodriguez-Duarte J, Dapueto R, Galliussi G, Turell L, Kamaid A, Khoo NKH, et al

Animal studies have also demonstrated that resveratrol significantly reduces inflammatory markers such as TNF- , IL-6, and IL-1

It involves the coordinated interaction of multiple biological processes, including: Cell migration to the site of injury Formation of new blood vessels (angiogenesis) Fibroblast activation Extracellular matrix remodeling Regulation of the inflammatory response Cytoskeletal organization For this reason, research is increasingly focused on combining peptides that possess distinct yet complementary mechanisms of action

More than three decades ago it was established that muscle activity leads to an increase in ROS production and concentration of free radicals [1,2]