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Vitamin D deficiency has been associated with an increased risk of death from cardiovascular disease, cognitive impairment in the elderly, severe childhood asthma and cancer

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Because AOD-9604 does not bind to growth hormone receptors in liver, muscle, or adipose tissue, it cannot trigger the metabolic pathways that mediate growth hormones counter-regulatory effects on glucose metabolism

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(2014) published foundational work demonstrating that NNMT expression in adipose tissue correlates with metabolic parameters in preclinical models
