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While HCR sequences are required for the expression of apoC1 gene in hepatocytes [23], ME-1 and ME-2 play a significant role in stimulating its expression in macrophages through the binding of the Liver X Receptor (LXR) via LXR response elements [24]

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Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties

In reports up to 158 pages long, the agency detailed the science behind the immune response risk in synthetic peptides, listed documented adverse events associated with the drugs and summarized the limited research on human subjects