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Only one study in patients with gastro-esophageal reflux disease (GERD) took the effort of comparing CLE to classical Ussing chamber experiments, which showed no differentiation between GERD and controls by probe-based CLE and no correlation of CLE findings and ex vivo permeability (51)

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The BDNF upregulation data suggests it's doing more than modulating GABA there's a genuine neuroprotective signal worth studying

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(Liu et al., 2017) demonstrated a significant association between serum MNAM levels and coronary artery disease, as well as left ventricular systolic dysfunction in Chinese patients (Liu M