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Intriguingly, a study postulated that a moderate increase of ROS levels may play a role in redox homeostasis by protecting the cell through a preconditioning process, which posits that exposure to a small insult allows better tolerance of a subsequent larger insult

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Although cyst(e)ine levels did not fully recover, presumably because of impaired cystine reabsorption due to sustained tubular injury by sulfasalazine, , cystine levels tended to increase in the sulfasalazine group

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& Boer, J