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Mothet, J

Arndt D

Escitalopram is first metabolized via N-desmethylation to S-desmethylcitalopram by CYP3A4 and CYP2C19 (Kobayashi et al., 1997), and this metabolite is subsequently demethylated mainly by CYP2D6 to form S-didesmethylcitalopram (von Moltke et al., 2001)

Reported side effects Most people report minimal side effects

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Additionally, several rare pathogenic variants in SCN9A have been identified in patients carrying small fiber neuropathy [92], further underscoring the critical involvement of this gene in potentiating the mechanism of neuropathic pain