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Free Radical Protection*
Consequently, protein fragmentation and generation of many protein oxidation products, which can cause damage to other biomolecules, may occur [53,61,62]
We measured glutathione, glutamate and glutamine concentrations in the anterior cingulate cortex (ACC), left insula, and visual cortex using 7T proton magnetic resonance spectroscopy (MRS)
Given these multiscale findings, spatiotemporal level changes in brain GSH and other antioxidants may indicate that certain brain regions, in particular, metabolically expensive hub regions (e.g., posterior cingulate cortex) (Badhwar et al., 2017, Tomasi et al., 2013), are more vulnerable to aging-related OS (Badhwar et al., 2017, Hahn et al., 2022, Tomasi et al., 2013)
doi:10.1016/j.bioactmat.2023.04.023 85
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