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Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a Phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability

10.1055/s-0042-107243 Exp

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While NSAIDs reduce pain and inflammation, they also interfere with tissue repair processes

We have also found that desnutrin/ATGL is downregulated in ob/ob and db/db mice, further supporting a role for the enzyme in fat breakdown and suggesting a possible contributory role in the development of obesity (130)