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Inflammatory mediators not only damage testicular architecture by impairing the blood-testis barrier [13] but also disrupt the function of Leydig cells, which are responsible for testosterone synthesis [12, 27]
It is essential to start with a lower dose and gradually titrate up to assess tolerance, particularly for patients with severe ME/CFS who may be highly sensitive to metabolic shifts

Zhang C, He J, Huo Y, Liu L, Xie Y, Meng Y, et al

As we age, the body's collagen production decreases, leading to fine lines, wrinkles and sagging skin

PMID: 19418208

In: Andersen, F.L
