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The wild type, but not a mutant form of -synuclein is degradated by CMA, suggesting that this mechanism is important in the formation of -synuclein aggregates during PD [114]

It is important to note that while these genetic technologies can identify how genetic variations relate to drug responses, drug responses are influenced by a bunch of other factors, such as protein expression, how the body metabolizes drugs, and epigenetic regulation

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Therefore, both the levels and activity of IGF-IR are positively correlated with tumor progression

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J Biol Chem 2000;275(14):10597-10603