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In IBD, an imbalance in the redox system is caused by excessive production of ROS in colonic tissues, shown by oxidative changes to lipids, proteins, or DNA (31)

Cell Metab (2006) 3(3):17785

One innovative strategy employed the layer-by-layer assembly technique to coat liposomes loaded with IL-12 ( Figure 3B ) ( In vitro fluorescence microscopy revealed distinct behaviors: liposomes with HA as the terminal layer were effectively internalized by two cancer cell lines, whereas PLE-coated liposomes bound to the cell surface membrane without significant uptake across multiple cell types

Nutrients (2019) 11(2):482

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In breast cancer, RNF5 loss is associated with increased ASCT2 expression, finally leading to poor patient outcomes, and poor response to paclitaxel (Jeon et al., 2015)