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Mol Pharmacol 56:10251030

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In cell culture experiments, it exhibits similar effects to SAHA, as it has the capability to impede cancer cell growth and induce both DNA double-strand break damage and cell apoptosis simultaneously (Pojani and Barlocco, 2021)

Under normal conditions, systemic iron homeostasis relies on the coordinated expression of transferrin (TF), ferroportin 1 (FPN1), transferrin receptor 1 (TfR1), and liver-produced iron regulatory proteins (ROCHETTE et al., 2022)

Zinc is also an inhibitor of NADPH oxidases that catalyze the production of the singlet oxygen radical from oxygen by using NADPH as an electron donor