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Further evidence supporting the potential in situ deleterious effects of APAP in brain comes from studies showing that APAP increases neuronal CYP2E1 enzymatic activity and protein levels, leading to neuronal cell death through mitochondrial-mediated mechanisms that involve cytochrome c release and caspase 3 activation (130)

279 , H1490H1501 (2000)

It acts as a coenzyme in the mitochondria the powerhouses of the cell where it helps convert glucose into ATP, the cells usable form of energy
10.1002/path.2277 [DOI] [PMC free article] [PubMed] [Google Scholar] Xue X

Accelerating drug discovery

(Clinical Nutrition & Dietitics), NDEP, Course in Maternal Infant Young Child Nutrition.Diploma in Sports Nutrition, Diploma in Diabetic educator, FODMAP Specialist Kolkata BIENETRE CLINIC, Kolkata Dr Vijeya Lakshmi Chakravarthy General Physician 3 Years MBBS Bengaluru PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru Ms
