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1985 Oct;41(4):353-6

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Uncovering the MET-TRIB3-FOXO1 axis: A novel target in MET-driven hepatocellular carcinoma: Editorial on MET promotes hepatocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation
An Imaging Biomarker of Tumor-Infiltrating Lymphocytes to Risk-Stratify Patients With HPV-Associated Oropharyngeal Cancer

Therefore, the elevated nicotine levels observed in NtGSTU10 -expressing yeast cells may reflect indirect effects, such as binding or detoxification-related processes, rather than direct membrane transport activity
It's also why some budget products require higher concentrations to match results from premium formulations at lower percentages