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Changes in the BBB associated with Alzheimer's disease primarily include endothelial abnormalities such as reactive gliosis, mitochondrial damage, alterations in the extracellular matrix, disrupted tight junctions, and both molecular and functional changes in astrocytes
ANGPTL3 Inhibition, dyslipidemia, and cardiovascular diseases
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However, this adverse effect occurred less frequently than GI disturbances, and the mean cholesterol concentration in the study population was only marginally higher than baseline values
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arundinis strain CBMAI 2109 showed a 0.5% reduction in PET mass, whereas strain CBMAI 2110 achieved a 0.16% reduction
