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Allicin induces the upregulation of ABCA1 expression via PPARgamma/LXRalpha signaling in THP-1 macrophage-derived foam cells

Furthermore, chronic exposure of endothelial cells to Hcy accelerated the rate of cellular senescence through the redox pathway suggesting that oxidative stress could increase the production of vascular cell senescence proven by increased expression of two surface molecules such as intracellular adhesion molecule-1 (ICAM-1) and plasminogen activator inhibitor-1 (PAI-1), factors implicated in the pathogenesis of atherosclerosis [73]

J.MentleinR.TillmannB

2023;66:S762S763
Extracellular matrix-mediated regulation of cancer stem cells and chemoresistance

Cognitive and physical lifestyle factors may also be influential, given that sedentary behaviour is associated with an earlier onset and greater severity of symptoms [142]
