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Indeed, optogenetic activation of vlPOA VGAT neurons potently induced hypothermia in Vgat-cre mice, as did chemogenetic silencing of DMH VGAT neurons, both of which induced neuroprotection by inhibiting cerebral reperfusion injury

Serious Risks & Warnings Not FDA-approved: Melanotan II is not an approved medication
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documented case reports in the medical literature mean this is a recognized adverse event class