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PM in the oropharynx enters the gastrointestinal tract through swallowing and disturbs the intestinal microecology, manifesting as changes in the composition and diversity of the intestinal flora

Several preclinical studies showed that intranasal insulin treatment leads to an improvement in mitochondrial functions as well as a reduction of dopaminergic cell death in a rat 6-OHDA model of PD [197, 198]

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients

You can enhance your bodys own peptide activity through nutrition, exercise and lifestyle strategies, often with fewer risks and side effects than synthetic compounds

NLRP3 is activated after experiencing upstream signals such as K + and Cl efflux, mitochondrial dysfunction, the release of reactive ROS and mtDNA, and the release of cathepsin B