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Description
The HTS involved coexpressing metabotropic glutamate receptor 8 (mGlu8) and GIRK1/2 channels, and the primary screening set yielded around 2000 hits
Some peptides, particularly GLP-1 and GIP receptor agonists, directly influence appetite regulation, blood sugar control, and fat metabolism

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Development 133 , 28652874 (2006)

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