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Several molecular mechanisms of action including induction of oxidative stress as characterized by reactive oxygen species production and lipid peroxidation, induction of p53 signaling and cell cycle arrest, down-regulation of proto-oncogenes and anti-apoptotic proteins, and activation of both intrinsic and extrinsic pathways of apoptosis
For bovine viral diarrhea virus and yellow fever virus, glycosylated IFN- showed a stronger effect 35
*Correspondence: Kenneth B
The potency of PAI-1 activity in thrombosis is sufficient for the use PAI-1 inhibitors as therapeutic agents for thrombosis treatment [7, 83,84,85]
The study demonstrated that metformin treatment enhanced paraoxonase activity, thereby ameliorating oxidative stress in the diabetic mice
