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The primary iteration, exemplified by hereditary hemochromatosis and juvenile haemochromatosis, predominantly arises from genetic perturbations, which attenuate hepcidin levels and enhance bodily iron absorption, instigating excessive iron deposition within internal organs [767, 770773]

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[DOI] [PubMed] [Google Scholar] 163.Reiter R.J., Welsh M.G., Vaughan M.K