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mitochondria play a pivotal role in intrinsic pathway of apoptosis [38]

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This is the theoretical basis for endogenously supplied gamma-glutamylcysteines ability to raise GSH levels, as being the product of the GCL enzyme, it can be taken up by cells intact, where it feeds directly into glutathione synthase to be converted to glutathione, effectively bypassing the dysfunctional GCL

Microb Cell Fact 12(1):87 Ayala A, Muoz MF, Argelles S (2014) Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal

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Advantages are: lowering testosterone and is also a diuretic (water pill) which can decrease swelling and water weight), it also blocks aldosterone at the aldosterone receptor unlike flutamide