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Nitisinone increases melanin in people with albinism Wednesday, February 20, 2019 Nitisinone increases melanin in people with albinism A small pilot clinical study at the National Eye Institute (NEI) suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor vision

This hormone is crucial in determining skin pigmentation and protecting against UV damage

Most protocols run weekly, with some clinics using twice-weekly or every-other-week schedules depending on the formulation and the patient

[DOI] [PMC free article] [PubMed] [Google Scholar] 169.Valenti L et al

There was an Indian fortification when the first settlers arrived at Norwalk
