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Patients should stop tirzepatide and seek immediate medical care if they experience severe, persistent abdominal pain (which may indicate pancreatitis), symptoms of gallbladder disease (right upper quadrant pain, fever, jaundice), persistent vomiting leading to dehydration (which may cause acute kidney injury), or signs of severe allergic reaction

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Chu, A., & Wadhwa, R

Pinch the skin at the injection site between your thumb and forefinger to create a fold of tissue about one to two inches wide

Substrate-specific inhibition of organic cation transporter 1 revealed using a multisubstrate drug cocktail

Ethics approval and consent to participate This study was reviewed by the Natural and Non-prescription Health Products Directorate (NNHPD), Health Canada and a research ethics board, which granted ethics approval in December, 2014