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[51] revealed that IGF-1 significantly downregulated the PI3K/Akt signaling pathway, cell adhesion/endothelial stromal cell receptor pathway, T and B cell signaling pathway, and cytokines storm and inflammatory factors

FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair

Participants are allowed to withdraw from the study at any time

While the quantitative role of NRK1 in NAD + production in the kidney remains unknown, this enzyme is expressed at high levels in the renal proximal tubule (36)

Artificial intelligence (AI)-assisted spatial metabolic imaging and response modeling have been employed to dynamically predict drug responsiveness across distinct tumor regions, providing a robust foundation for the development of metabolism-guided combination strategies [132]

McChesney JA, Northup PG, Bickston SJ (2003) Acute acalculous cholecystitis associated with systemic sepsis and visceral arterial hypoperfusion: a case series and review of pathophysiology