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and after intracerebral hemorrhage, clathrin acid improves ferroptosis through cysteine 66 modification of the GPx4 site after intracerebral hemorrhage, alteration enhances its enzymatic activity by alkylation modification, thereby inhibiting neuronal ferroptosis, and the Irg1/cleroconanic acid/GPx4 axis may be a future therapeutic strategy to protect neurons from ferroptosis after intracerebral hemorrhage

Analysis of influencing factors on the occurrence and development of gastric cancer in high-incidence areas of digestive tract tumors based on high methylation of GPX3 gene

doi: 10.1371/journal.pone.0011951, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 172.Sergi CM

The stroma is of utmost importance to the tumor microenvironment, contributing to cancer initiation, progression, metastasis, and therapeutic resistance 22

However, its involvement in ferroptosis is less well elucidated