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A clinical trial demonstrated that 8 weeks of consecutive magnesium supplementation significantly increased sleep duration and reduced sleep latency in elderly individuals.10 In addition, magnesium treatment for patients with alcohol dependence (who often have magnesium metabolic disorders) using the PSQI significantly reduced the sleep onset latency, which decreased from an average of 40.6 min before treatment to 21.7 min ( P =0.03), and improved the subjective sleep quality.81 Interestingly, a study identified a negative correlation between magnesium intake and daytime sleepiness in women, but not in men

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Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes

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1 The circadian clock regulates mitochondrial complex I respiration, related to Fig
