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doi: 10.1096/fj.202300907 17 GubbelsASpivackLLindheimSRBhagavathB

Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis
Free radicals are unpaired electron pairs
NAD+ supports cellular energy production and is one of the most studied compounds in the longevity space

Given the foundational role of NAPDH in ferroptosis defence, this leads us to question whether ferroptosis may be unleashed by metabolic dysregulation leading to altered carbon flux and failure to supply enough NADPH to regenerate GSH and other ferroptosis suppressors
