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Dehydration often leads to cramping and spasms, especially during exercise

As already mentioned, anti-angiogenic therapy can promote tumor invasion and metastasis in pre-clinical cancer models, which might be triggered by increased hypoxia due to vessel depletion

doi: 10.1158/0008-5472.CAN-07-5840

Ingesting any vitamin can definitely improve skin health, but most of the benefit will be directed to vital organs before the skin
