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To view a copy of this licence, visit About this article Cite this article Faria, A.M., Valerio, C.M., Barcellos, C.R

In cellular models of ALS the RNA processing gets severely impaired upon oxidative stress, in turn causing the mis-localization of TDP-43 and FUS ( Another major factor contributing to the pathophysiological mechanisms in ALS is excitotoxicity, triggered by excessive postsynaptic glutamate receptor stimulation