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10.1056/nejmc1616623 N Engl J Med
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Nutrition or obesity A diet high in unsaturated fat increases susceptibility

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e177 Koppula P, Lei G, Zhang Y, Yan Y, Mao C, Kondiparthi L, et al
PT2385 is one of the very few HIF-2 inhibitors investigated in preclinical models of GBM and works by preventing allosteric heterodimerization with HIF-1 when it binds to HIF-2 PAS-B domain (156)
