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Of interest, the down-expression of ACC2 results from an epigenetic process linked to histone deacetylation at the ACACB promoter by Sirtuin 1/6 that are activated by high cytosolic NAD + levels associated with enhanced FAO and reduced glucose metabolism

Classification criteria were the number of patients showing (1) improvement in pneumonia lesions, (2) worsening of pneumonia lesions, (3) stable pneumonia lesions, and (4) resolution of pneumonia lesions

doi: 10.2337/diabetes.49.5.677, PMID: [DOI] [PubMed] [Google Scholar] 19.Drosatos K, Schulze PC

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