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First demonstration that activity can independently influence the expression of synaptic AMPA receptors and NMDA receptors

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TB-500 is studied primarily for its effects on actin polymerization and cell migration

pmc.ncbi.nlm.nih.gov/articles/PMC6073405 Pickart L, Vasquez-Soltero JM, Margolina A

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Intermolecular hydrogen bonds with water can create a hydration shell that weakens membrane partitioning by increasing peptide polarity and reducing the octanolwater partition coefficient [81]