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FRDA patients exhibit decreased blood plasma-iron levels and cytosolic ferritin levels shifted to higher concentration of its light-chain than heavy-chain counterparts in the dentate nucleus, indicating iron transport from the circulation but bypass of cytosolic storage (Koeppen et al., 2007

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IF was examined using an SP8 Confocal Microscope and LAS X Image processing software (Leica)

aureus in check, are more sensitive to the remaining AMPs than S

To confirm the binding affinities of the two bispecific nanobody constructs, we also performed surface plasmon resonance (SPR) measurements to determine kD value (Fig