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Concentrations vary significantly among species, with some varieties containing extraordinarily high amounts

Carretero and colleagues have also shown that increased GSH promotes growth of metastatic melanoma cells in the liver (Carretero et al., 1999)
Moreover, adeno-associated virus (AAV)-mediated PHGDH inactivation in the brain decreased tissue l-serine and glycine levels and impaired synaptic plasticity and spatial memory (60), demonstrating that reduced l-serine levels in the brain contribute to cognitive dysfunction

For the human GCL genes, the promoter enhancer regions of the two genes contain several elements able to respond to oxidants and electrophiles (Gipp et al., 1992

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Amino acid and protein modification by oxygen and nitrogen species
